Summary: Mitochondrial dysfunction causes muscle wasting in many diseases and probably also during aging. The underlying mechanism is poorly understood. We generated transgenic mice with unbalanced mitochondrial protein loading and import. by moderately overexpressing the nuclear-encoded adenine nucleotide translocase. https://www.storeanimalwiz.shop/product-category/rawhide-bones/
Cytosolic adaptation to mitochondria-induced proteostatic stress causes progressive muscle wasting
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