Background/Aims: New strategies are required to combat neuronal ischemia-reperfusion injuries. K6PC-5 is a novel sphingosine kinase 1 (SphK1) activator whose potential activity in neuronal cells has not yet been tested. Methods: Cell survival and necrosis were assessed with a Cell Counting Kit-8 assay and lactate dehydrogenase release assay. respectively. https://www.alarecre.com/Disney-The-Nightmare-Before-Christmas-Lock-Shock-and-Barrel-Art-AirPods-Pro-2nd-Gen-Skin-p101716/